Textbook of Drug Design and Discovery, Third Edition Review

Average Reviews:

(More customer reviews)but the content is excellent. For an practicing organic chemist learning medicinal chemistry, I have read/browsed many books, and have settled on this one and Wermuth's "The Practice..." as my 'A-team'.
Unfortunately, the paperback binding will crack & quickly compromise the retention of the pages, but that is not the authors fault. The content is what matters & if you are an Organic Chemist & want to learn Med Chem, I would strongly suggest you start here. I would compare this to the 'Burger' of the old days, before it became an unaffordable encylclopedia.

Click Here to see more reviews about: Textbook of Drug Design and Discovery, Third Edition

Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine.The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

Get 4% OFF

Click here for more information about Textbook of Drug Design and Discovery, Third Edition

Read More...

DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling Review

Average Reviews:

(More customer reviews)This book tries to combine a practical and theoretical point of view concering microarray expermiments and the data analyis thereof. This is a very honourable goal. Unfortunatelly, it fails. An indicator for this can already be seen in the low number of pages. This book has less than 140 pages (I exclude the last chapter and the appendix). It is clear, that it is impossible to discuss in detail this topic in this limited number of pages. Hence, during reading the chapters one gets the feeling, that one reads short essays which are stringed together. At no point the authors go into detail but give only a short idea and references.
I see no reason, why I should recommend this book to anyone. It is in its current form just immature. My prediction: There will be no second edition because even its basic substance is very weak.
Some words to the last chapter (systems biology). This is indeed the most interesting and best chapter of the book (35 pages) without going into details as the rest of the book. I think according to this chapter one realize under which premise this book was written. Unfortunatelly, combining buzz worlds in short essays is not enough for a good book. Sorry guys, I think you can do better!

Click Here to see more reviews about: DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling

Massive data acquisition technologies--such as genome sequencing, high-throughput drug screening, and DNA arrays--are in the process of revolutionizing biology and medicine. This concise, user-friendly and interdisciplinary guide to DNA microarray technology is an introduction and a reference for both biologists and computational scientists. The authors describe the underlying technologies and offer an awareness of the "noise" and pitfalls present in the data generated. They also provide an idea of the different data mining techniques and algorithms that are available to interpret data, and the advantages and disadvantages of each in differing situations.

Click here for more information about DNA Microarrays and Gene Expression: From Experiments to Data Analysis and Modeling

Read More...

Modeling Biological Systems:: Principles and Applications Review

Average Reviews:

(More customer reviews)This book is a complete dissapointment.
It does not offer any real scientific physical models which then can be transformed in an algorithm and being simulated but is is merely a conglomerate of several statistical procedures commonly used in Biology for interpreting data (maybe copied by the author and collected from other books, as nothing that he presents is new!). This book does not offer any scientific, fundamental insight in how to really model and simulate properly complex biological systems, it is also written in a very unscientific, popular style. The mathematical level corresponds to High-School and as the author says in the preface: "The process of modeling biological systems is certainly not a science, but neither is it as unconstrained as the creation of a work of pure art that is evaluated solely on its esthetic content". I think that nonsense speaks for itself. This author should rather write novels instead of cobbling something together that gets the label "scientific" on the cover.
The book is not trash, the author does have collected some of the simplest "models" there are to describe collections of data in statistical terms, but this has NOTHING to do with proper scientific numerical and mathematical modeling and even less with scientific Computing in the field of biological complex systems, e.g. how to simulate membranes, proteins using Quantum Chemistry or Molecular dynamics techniques.
All in all I judge this book as a complete waste of money and as completely superfluous.

Click Here to see more reviews about: Modeling Biological Systems:: Principles and Applications

This is the second edition of a textbook currently published by Springer for a course in mathematical modeling and computer simulation for biologists at the advanced undergraduate and introductory graduate level. The audience for this edition is similar to that of the previous one: advanced level courses in computational biology, as well as researchers retooling themselves. This new edition includes a CD-ROM with real examples of models as teaching tools.

Get 20% OFF

Click here for more information about Modeling Biological Systems:: Principles and Applications

Read More...

Biomedical Signal Processing and Signal Modeling Review

Average Reviews:

(More customer reviews)Good book for looking at the mathematics behind biomedical signal processing. If your going to use Matlab in conjunction with your study of this book, I used "Biosignal and Biomedical Image Processing: Matlab-Based Applications," by John L. Semmlow.

Click Here to see more reviews about: Biomedical Signal Processing and Signal Modeling

A biomedical engineering perspective on the theory, methods, and applications of signal processing This book provides a unique framework for understanding signal processing of biomedical signals and what it tells us about signal sources and their behavior in response to perturbation. Using a modeling-based approach, the author shows how to perform signal processing by developing and manipulating a model of the signal source, providing a logical, coherent basis for recognizing signal types and for tackling the special challenges posed by biomedical signals-including the effects of noise on the signal, changes in basic properties, or the fact that these signals contain large stochastic components and may even be fractal or chaotic. Each chapter begins with a detailed biomedical example, illustrating the methods under discussion and highlighting the interconnection between the theoretical concepts and applications. The author has enlisted experts from numerous subspecialties in biomedical engineering to help develop these examples and has made most examples available as Matlab or Simulink files via anonymous ftp. Without the need for a background in electrical engineering, readers will become acquainted with proven techniques for analyzing biomedical signals and learn how to choose the appropriate method for a given application.
An Instructor's Manual presenting detailed solutions to all the problems in the book is available from the author.

Get 17% OFF

Click here for more information about Biomedical Signal Processing and Signal Modeling

Read More...