5/24/2012

Textbook of Drug Design and Discovery, Third Edition Review

Textbook of Drug Design and Discovery, Third Edition
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but the content is excellent. For an practicing organic chemist learning medicinal chemistry, I have read/browsed many books, and have settled on this one and Wermuth's "The Practice..." as my 'A-team'.
Unfortunately, the paperback binding will crack & quickly compromise the retention of the pages, but that is not the authors fault. The content is what matters & if you are an Organic Chemist & want to learn Med Chem, I would strongly suggest you start here. I would compare this to the 'Burger' of the old days, before it became an unaffordable encylclopedia.

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Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine.The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.

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