Pharmacokinetic-Pharmacodynamic Modeling and Simulation Review

Pharmacokinetic-Pharmacodynamic Modeling and Simulation
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The author is well-known in the PK/PD modeling field. It is a reader-friendly book. It is very easy to understand. You would not be bored by the terminology. The author explained the theory and ideas by the simplest words. Actually, it is a very fun book. You are just like reading a story, not a boring science book.
This book is for students/professionals with adequate backgroup of PK/PD, math and statistics. It is especially useful for an entry level modeler or future modeler.
I love this book.

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A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. The purpose of this book is to present through theory and example how to develop pharmacokinetic models, both at an individual and population level. In order to do so, however, one must first understand linear models and then build to nonlinear models followed by linear mixed effects models and then ultimately nonlinear mixed effects models. This book develops in that manner - each chapter builds upon previous chapters by first presenting the theory and then illustrating the theory using published data sets and actual data sets that were used in the development of new chemical entities collected by the author during his years in industry. A key feature of the book is the process of modeling. Most books and manuscripts often present the final model never showing how the model evolved. In this book all examples are presented in an evolutionary manner.

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